What kind of neurotransmitter receptor is located on the motor end plate of a skeletal muscle fiber?

Acetylcholine, often abbreviated as ACh, is a neurotransmitter released by motor neurons that binds to receptors in the motor end-plate.

What kind of receptors are found at the motor end plate?

Cholinergic receptors are concentrated at the motor end-plate region of the sarcolemma in normal skeletal muscle. When the motor end plate is depolarized, the action potential is propagated to voltage-sensitive sodium channels in the adjacent sarcolemma.

What is the motor end plate of skeletal muscle?

Neuromuscular junctions, also called motor end plates, are specialised chemical synapses formed at the sites where the terminal branches of the axon of a motor neuron contact a target muscle cell.

Which neurotransmitter is released at the motor end plate?

neuromuscular junction

Embedded in the end plate are thousands of receptors, which are long protein molecules that form channels through the membrane. Upon stimulation by a nerve impulse, the terminal releases the chemical neurotransmitter acetylcholine from synaptic vesicles.

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What neurotransmitter is involved in skeletal muscle contraction?

The chemical message, a neurotransmitter called acetylcholine, binds to receptors on the outside of the muscle fiber. That starts a chemical reaction within the muscle.

What is the process of excitation?

The process of excitation is one of the major means by which matter absorbs pulses of electromagnetic energy (photons), such as light, and by which it is heated or ionized by the impact of charged particles, such as electrons and alpha particles.

Which would be the correct order for skeletal muscle contraction?

So, Correct answer is ‘Stimuli Neurotransmitter secretion →→ Excitation of T-system →→ Release of Ca2+ →→ Cross-bridges formation →→ Sliding of actin filaments →→ H band diminishes’

Which ion is important for muscle contraction?

The muscle contraction cycle is triggered by calcium ions binding to the protein complex troponin, exposing the active-binding sites on the actin.

Why is calcium important for muscle contraction?

Nerve and Muscle Function

Calcium’s positive molecule is important to the transmission of nerve impulses to the muscle fiber via its neurotransmitter triggering release at the junction between the nerves (2,6). Inside the muscle, calcium facilitates the interaction between actin and myosin during contractions (2,6).

What is depolarization of muscle?

muscle contraction

In muscle: Release of acetylcholine from the nerve terminal. The channels are opened by depolarization (an increase in membrane potential) of the nerve terminal membrane and selectively allow the passage of calcium ions.

What are the steps of muscle contraction?

The process of muscular contraction occurs over a number of key steps, including:

  1. Depolarisation and calcium ion release.
  2. Actin and myosin cross-bridge formation.
  3. Sliding mechanism of actin and myosin filaments.
  4. Sarcomere shortening (muscle contraction)
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What causes the receptors on the motor end plate to open?

The acetylcholine binds to the nicotinic receptors concentrated on the motor end plate, a specialized area of the muscle fibre’s post-synaptic membrane. This binding causes the nicotinic receptor channels to open and let sodium ions enter the muscle fibre.

When the nerve signal reaches the axon terminal What happens next?

Within a cell, action potentials are triggered at the cell body, travel down the axon, and end at the axon terminal. The axon terminal has vesicles filled with neurotransmitters ready to be released. The space between the axon terminal of one cell and the dendrites of the next is called the synapse.

What are the 7 steps of muscle contraction?

Terms in this set (7)

  1. Action potential generated, which stimulates muscle. …
  2. Ca2+ released. …
  3. Ca2+ binds to troponin, shifting the actin filaments, which exposes binding sites. …
  4. Myosin cross bridges attach & detach, pulling actin filaments toward center (requires ATP) …
  5. Muscle contracts.

What are the 5 steps of muscle contraction?

Terms in this set (5)

  • exposure of active sites – Ca2+ binds to troponin receptors.
  • Formation of cross-bridges – myosin interacts with actin.
  • pivoting of myosin heads.
  • detachment of cross-bridges.
  • reactivation of myosin.

What are the 6 steps of muscle contraction?

Sliding filament theory (muscle contraction) 6 steps D:

  • Step 1: Calcium ions. Calcium ions are released by the sarcoplasmic reticulum in the actin filament. …
  • Step 2: cross bridge forms. …
  • Step 3: Myosin head slides. …
  • Step 4: skeletal muscle contraction has occurred. …
  • Step 5: Cross bridge breaks. …
  • Step 6: troponin.
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Motorization